How are you supposed to determine the correct dosage of methylation supplements for yourself? In particular I'm wondering about methylfolate. My understanding is that folate is water soluble, so toxicity probably isn't a big concern, but people have taken anything from mcg's of the stuff to several tens of mg's, so how do you determine the right dose for yourself? Obviously how you feel will guide things somewhat, but is there a more objective means of judging? I've read that you can over methylate as well, so how do you judge when you are going from under methylating to over methylating.