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Methylation cycle and Vitamins ???

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by ramkishore, Jul 2, 2014.

  1. ramkishore

    ramkishore

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    Hi

    I want to know which vitamins (especially B vitamins) are used at different parts of methylation cycle. I hope there are four cycles which together form methylation cycle as per Amy Yasko.

    i just want to know which forms of B vitamins are used readily by body during methylation.

    Regards
  2. PeterPositive

    PeterPositive Senior Member

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    Hi,
    to make a long story short the main B vitamins involved in the methylation cycle are B12, B9 and B6, as exemplified by this diagram:

    [​IMG]

    For a more in depth discussion you can check Dr. Ben Lynch's presentation on YouTube:

  3. ramkishore

    ramkishore

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    wow...great diagram. The simplicity side of complexity.
    thanks for that diagram.

    which forms of B6 and B9 should I take?

    I know its p5p for b6. but why should i not take direct form of B6? If methylation is wrong, is B6 in direct form not usable? Same question with B9?

    Warm Regards
    Kishore
  4. PeterPositive

    PeterPositive Senior Member

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    Normally the best forms are the active forms:
    B9 -> Methylfolate (e.g. Metafolin or Quatrefolic)
    B12 -> MethylCobalamin
    B6 -> P5P is the active form. You can also use regular B6 and let your body activate it. It may not work for everyone though. Some docs use both forms.
    ramkishore likes this.
  5. ramkishore

    ramkishore

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    @PeterPositive
    Lastly NAD and NADH confusion. which one should I use?
    Last edited: Jul 3, 2014

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