Wow. I thought I was totally up to date on all the treatments and investigations for ME I'm missing out on - anti-virals for herpes viruses, tick-bourne diseases, gut infections, SIBO, leaky gut... And now I come here and find I probably have a methylation problem because my B12 is low despite eating a high protein diet and taking methylcobalamin. This stuff is so much more complicated than anything else I've read. And I read EVERYTHING. My brain is stuck. You guys have had your genes tested for this? I've been sick for 8 years and had no proper testing at all, beyond the stupid mainstream medical. I really want a Functional Medicine doctor to take me in hand. I can't do it on my own any more. Please help me, someone.