Methylation and inflammation

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by place, Aug 16, 2012.

  1. place Be Strong!

    Messages:
    193
    Likes:
    18
    US
    Hey everyone,
    During my meth journey I have encountered many issues and have been able to solve them with everyones assistance. Very thankful for people much smarter than I.

    I have discovered that with use of methylation that will get inflammation. I thought it was histamine but I don't think it is as the IC that flare up. I looked up IC and they say it is inflammation.

    I have tried cystine and potassium... nothing.

    My questions.... If histamine is converted in the meth process, what else could be causing the inflammation?
    The inflammation increase as my energy output increases.

    Thanks!
  2. dmac

    Messages:
    32
    Likes:
    4
    you said,
    "I have discovered that with use of methylation that will get inflammation. I thought it was histamine but I don't think it is as the IC that flare up. I looked up IC and they say it is inflammation."

    you thought it was the histamine causing the inflammation?
    what is IC?

    do you think the increased inflammation could be the detox from the release of toxins due to the methylation?

    you said
    "My questions.... If histamine is converted in the meth process, what else could be causing the inflammation?
    The inflammation increase as my energy output increases. "

    if the histamine is converted to what?
    do you mean if the histamine is lowered through methyl it would not cause the inflammation?

    So the more energy you get the worse the inflammation?

    trying to understand this better

    thanks

    denise
  3. place Be Strong!

    Messages:
    193
    Likes:
    18
    US
    Denise,
    Yes, So this week I have tried to keep the inflamtion/ or what ever it is up by running or being active. Normally if I chilled and took advil, it would be gone in 2-3 days. If histamine is converted or used in the methyl cycle than it may be something else.

    "do you think the increased inflammation could be the detox from the release of toxins due to the methylation?"
    Could be, what should I test to varify?


    I have been trying to keep it going to test things out. The following has not done anything for my interstitial cystitis:
    -Allergy meds such as bendryl/singulaur
    -more Potassium
    -cystine

    Next to try is Anti-inflamitiories: currently trying this afternoon is Lodine

    Fortunately, I have a small pharmacy in my house =(

  4. dmac

    Messages:
    32
    Likes:
    4
    I am new to this. I have been trying to heal gut and doing mercury chelation so new at methylation.

    So let me see if I understand.

    If one has LOW methyl and HIGH histamine,
    when on the methyl treatment,
    we try to raise the methyl, which would lower or convert or use , as you say, the histamine so it would be less likely to be causing the inflammation, unless..

    you are eating high histamine foods like spinach, tomatoes, avocado, etc,
    what about the sun (due to high histamines I am allergic to the sun and can cause inflammation reactions )

    eating or having supplements that have gluten in them? i am not sure.

    do you have mercury problems? use dmsa?
    had/have fillings, your mom have fillings? vaccines?

    if you do and also have sulfur problems b/c of the mercury, taking the cysteine b/c it is sulfur and can re distribute and mobilize the mercury and you can feel worse.
    maybe high sulfur foods and supplements?

    raising the methyl can release toxins, pathogens and metals/mercury and that could be causing inflammation reactions.

    like your moots says, we have to keep going. I know my detox is hell but i have to go through it to get to the other side. maybe go slower, reduce what you are doing?

    what are you doing? what treatments?

    what sx are you having that feel like inflammation?

    i am really battling foods with histamines and sulfur as well.
    maybe try an elimination diet from sulfur and histamine foods and see if that helps.

    there are list of high sulfur foods and high histamine on line

    the high sulfur list is from living new zealand. something . i will get and bring back here for you

    denise
  5. dmac

    Messages:
    32
    Likes:
    4
  6. dmac

    Messages:
    32
    Likes:
    4
    sorry, one thing that might help if you have issues with sulfur foods/mercury is molybdenum .

    i am big on mercury b/c I think it is so often over looked and if not removed properly with dr cutter protocol many suffer while they are doing other treatments and think it is the treatment making them sicker but it can be the re distribution of mercury, if this applies to your history

    thanks
    denise
  7. place Be Strong!

    Messages:
    193
    Likes:
    18
    US
    dma, thank you for the suggestions. I will have to make a list to tackle.

    Well, last night I took Lodine, after a few hours nothing. Then I took copper and probotics...... it went away! Must repeat testing again.
  8. place Be Strong!

    Messages:
    193
    Likes:
    18
    US
    Ok, would it be weird if it was copper that fixed it? Went running, got my IC, tried the copper and its gone. Really? What does everyone know about copper?
  9. nanonug Senior Member

    Messages:
    1,247
    Likes:
    366
    Virginia, USA
    To avoid having the Justice System using your own posts against you, you may want to write "methylation" instead of "meth" if you know what I mean! :)

    Anyway, methylation increases adenosine which results in mast cell degranulation. If your issue is mast cell related, then increasing methylation may not be what you are looking for.

    By the way, Interstitial Cystitis is one of the symptoms of Mast Cell Activation Syndrome.
  10. place Be Strong!

    Messages:
    193
    Likes:
    18
    US
    ha-ha, Nanoun, as I was reading it, I thought the same thing! Lord, someones going to surprise me with an "Intervention!" Very prevalent in rural Ohio.

    I have no idea why the copper would solve this issue. I honestly took it per chance. I had some skin itching a while back and someone recommended copper. I took it but was not sure it solved the issue. However; with the IC, it has worked twice within an hour of taking it. Moreover, I get the IC when I have been exerting heavy energy.

    How has your treatment been going? Very interested in Mast cell theory. It fits me well as a dx.
  11. nanonug Senior Member

    Messages:
    1,247
    Likes:
    366
    Virginia, USA
    Here's one possibility:Inhibition of mast cell histamine release by copper.

    I am far from cured and, right now, with the pollen count elevated where I live, it's been tough. But I am definitely better that I was just a few months ago. In any case, I am still under-medicated. I am hopping to see a mast cell specialist in September to be finally formally diagnosed.

    My suggestion would be to contact The Mastocytosis Society and ask to be referred to a specialist in your neck of the woods. The lady below was the one that told me about the specialist in Virginia:

    Valerie M. Slee, RN, BSN, Chair
    Board of Directors
    Liaison, Medical Advisory Board
    Patient Referral Coordinator
    The Mastocytosis Society, Inc.
    23 Camelot Dr
    Shrewsbury, MA 01545
    Phone: 508-842-3080
    Fax: 508-842-2051
    Email: vmslee@aol.com
    www.tmsforacure.org

    Good luck!

Share This Page