Merck holds the largest patent on Metfolin (L-methyfolate) which it markets, along with other B vitamins, as a medical food called Metanx and is only available by prescription. Merck has sublicensed PamLabs to use and market in the supplement industry (I believe they have sublicensed to others by now). There was one company, Brookstone, that was marketing a product that was in their terms identical to L-methyfolate per the ingredients list, but in fact it was not even close as it was a racemic mixture of an active isomer and non-active isomer which made it very unstable and had a short shelf life (I'm sure is worded better somewhere else). This product had a shelf name of Focolast, but Merck and PamLab's took them down pretty quickly.
The product you reference above looks to be a different product than Metfolin or L-Methyfolate. The Quatrefolic version uses glucosamine salt, where as Mercks version uses a calcium salt? This could potentially create an interesting conversation as the difference in salts could effect how it is delivered into the body. Could it potentially effect it's ability to cross the blood brain barrier??? Richvank or Fredd would be the go to people to discuss this. You may want to PM them and ask as a knowledgable answer to the differences in these to could save someone from wasting their money. I'm glad you brought this up!
