I am new to this forum and have learned so much already from perusing thru many threads. I wanted to know if anyone else has tried the Metabolic Maintenance 10mg 5-MTHF to see if it is as reliable as the Solgar Metafolin? Today just started my third day of taking one capsule...10 mg...per day. I understand that many of you may not take this high of a dose but maybe some of you do and who have tried this brand. I have both fatigue and depression issues. I've read other posts that studies on Deplin had a better antidepressant response with 15mg as opposed to the 7.5mg so I am going to go up to the 15mg. I seem to have always had a high tolerance for supps so I really have no fear in upping my methylfolate to 15mg's. I also have Solgar Metafolin so I can just dose and extra 4800mg with that rather than measuring out half a capsule of the MM. I need to try to tackle this depression that I have had for quite some time and my fatigue that comes along with it. I'm taking SAM-e too, 1200 mg's per day. I took SAM-e in the past and went up to 1600 mg's per day with no effect in relieving my depression. So hopefully the addition of the methylfolate will kick things in gear. I shall find out. Also taking adenosyl and methyl B-12's as well as P5P and Douglas Labs B-complex and extra potassium which does help with not only post exercise crashes but also healing type symptoms from starting up on this protocol. Atleast one benefit I have noticed so far <only been on this protocol for about a week> is that my skin looks and feels smoother. I had bad acne in my teen years and to this day I still have adult acne breakouts but I am noticing a positive change in the texture of my skin so I must have ramped up my new cell growth. The MM brand is expensive but actually it is cheaper on a per mg basis for those who are taking this much methylfolate but I would like to know if anyone has tried this brand and if they have had success with it. Thanks for listening and so glad I have found this forum!