I take pregnenolone also thx. I take it to make progesterone to balance out the estrogen from the DHEA. I cannot take progesterone or much pregnenolone...it causes me to retain water and raises my b.p. I take 75mg DHEA and 30mg pregnenolone. It is more reasonable to take 100mg pregnenolone and 25mg DHEA but that does not work for me. There are others like me who need this topsy turvy ratio (more DHEA than pregnenolone). I am not an only - just an almost-only.