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Melatonin

Discussion in 'General Treatment' started by arx, Jun 19, 2012.

  1. taniaaust1

    taniaaust1 Senior Member

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    yeah, one shouldnt be on benzos unless one does really need to be. If the active Bs are over stimulating you to the point where its causing you sleep issues, it may be wiser to cut back on the Bs if that is going to avoid you needing to take a benzo. Benzos should be last resort if you need to take something for sleep issues.

    But for those who do need benzo for relief.. they can be such a real relief and not all have issues with them.

    Be aware that some ME/CFS specialists see small doses of Clonazepam.. protective of our brains (some specialists believe they protect our brains from neurotoxcity).
  2. taniaaust1

    taniaaust1 Senior Member

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    Its very interesting how we all get different responses to things. CIRCADIN slow release melatonin, I found to be worst (no effect at all on me) then any other kind of melatonin I tried.

    This is a good example of how if something doesnt work.. it may be worth trying another kind or brand.
  3. arx

    arx Senior Member

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    Yes, not taking any benzos and also cut back on the active Bs for now. Melatonin also seems to be working. I just have a doubt about the dosage and any side effects and long term effects. I'm taking 1.5 mg daily.

    And yes, also read about the Clonazepam in the recent article posted by Cort.
  4. Allyson

    Allyson *****

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    I have heard that melatonin is pretty safe long term but no real details on that
    I would be careful of the clonazapam though as that is definitely habit forming
    and is in the same family as valium - diazeapam
    I only take it as a last resort as it works quickly
    arx likes this.
  5. Rory_5

    Rory_5

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    I spoke with a doctor re: my severe insomnia. He advised I could take as much melatonin as I needed (safer than not sleeping at all) and then try to taper off. I went up to 80 mg to get a decent night, then cut to 70. I think tonight I'll try 60 and see how that goes.
    Sherlock likes this.
  6. Sherlock

    Sherlock bicarb for exercise recovery and taming candida

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    Hi, Rory. Did the doc say why it took so much for you? (I have no effect from 30 mg, maybe I'll try higher after reading this.)
  7. arx

    arx Senior Member

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    Wow, that is a lot!

    With Melatonin, I get weird vivid dreams and feel really groggy the next day. What about you guys?
    Allyson likes this.
  8. Rory_5

    Rory_5

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    He didn't say why exactly, but he was very confident it would work. And it did, and I am grateful because I had lost all function as result of the insomnia. Sleep meds on their own did little for me. I also use 5HTP, been using that for some time. I have weird dreams too, I think it's a combination of melatonin, 5HTP, and the anxiety all this has caused.

    The doctor added he had one patient, a middle aged woman, who needed 120 mgs. She gradually tapered down, as I am hoping to do.
  9. taniaaust1

    taniaaust1 Senior Member

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    Kind of scary to hear a doctor is telling patients to trial in amounts this much as Im sure no safety studies would of been one on amounts anywhere near that much. Melatonin is a hormone.. who knows what long term affects such huge doses could do.

    Once when I was sucidial, I tried to OD on a whole bottle of melatonin ..which actually had no affects or side effects on me at all (It didnt even help me to to sleep that night.. i went something like 36-48 hrs without sleep), so yeah from that I know melatonin can be quite harmless... but large doses long term.. I wonder. Maybe putting such large doses in the body would cause ones own body to produce even less of it?
  10. Rory_5

    Rory_5

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    Absolutely right. That's why I'm trying to taper off ASAP. Still, it's definitely been the lesser of two evils so far... the insomnia was so bad, I was fully expecting to be hospitalized.
    taniaaust1 and ggingues like this.
  11. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    i have tried 30-40mg once and didnt really do much. I have read that high doses over 20mg are used for cancer treatments and immune disorders but i havent commonly read about it though.

    cheers!!!
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  12. Sherlock

    Sherlock bicarb for exercise recovery and taming candida

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    AFAIK, there is no negative feedback with melatonin, as can occur with some other hormones.
    taniaaust1 likes this.
  13. Sherlock

    Sherlock bicarb for exercise recovery and taming candida

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    It'd seem logical that either the melatonin isn't working in some people, or else it isn't getting absorbed.

    I'll add that I had tried it for sleep long before getting sick, when it first came out. It did nothing back then for me either.
  14. Rory_5

    Rory_5

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    Then hopefully my taking 60 mg per night for the foreseeable future won't be a problem down the line
  15. Sherlock

    Sherlock bicarb for exercise recovery and taming candida

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    As for myself, I wouldn't take the same hormone (or supplement, or drug like benadryl) day after day after day. If it turns out that a supplement or drug was too much, at least the system can have a day off now and then to try and clear itself for self defense. I'd even think the same for a multivitamin.
  16. Allyson

    Allyson *****

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    Rory i have read that it makes mo difference how small adose of melatonint you take - ie a larger dose will be of no more use thatn a smaller one
    i take 2mg per night of the circadin and it works plretty well overall
    i have taken up to 6 mg of othr types and no ...did not find it helped more

    also re clonazepam which i take when i wake and can't get back to sleep i have found even a tiny bit helps - say about an eight of a 2 mg tablet does the trick ususally and eventually - it takjes alittle while to work.
  17. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Other benefit of melatonin is that it is a strong antioxidant especially for the brain and helps reduce high levels of dangerous nitric oxide, which b12 is used for as well. Doses maybe more importants when used for this purpose and for strengthening the immune system. one site cautions high doses of melatonin if one has an auto-immune condition.
    http://suite101.com/article/melatonin-in-autoimmune-disease-a19378
    taniaaust1 likes this.
  18. taniaaust1

    taniaaust1 Senior Member

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    it does seem to be a drug in which once one hits the dose which works for oneself.. taking more wont do much else. In my own case 2mg used to work but my sleep issues worsened over time and the 2mg stopped working.. but 3mg (which didnt do anything more then 2mg did originally) was working for me. So I then just started taking that dose.

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