Deconditioning is Not a Problem in ME. Orla, I totally agree. This is, at best, bizzare that Dr. Bateman says "not knowing how or not wanting to exercise is a human condition. It has nothing specific to this illness." As we discussed on another thread, it is very hard for the two of us, and many pwME, to not exercise. My cousin who has ME used to be an elite runner. She was physically unable to run for a long time. She has been doing short runs now for a few years because she feels she emotionally couldn't handle not running, even though it makes her physically sick. I worry that she has made her disease a lot worse with this practice. I had an arm cast in high school and I was totally amazed when it came off in six weeks that the muscle had just atrophied to nothing. In contrast, after 7 years of not exercising, my muscle mass has decreased only moderately. Deconditioning is not a factor worthy of attention in ME.