I just seem to have stumbled upon something that is helping me a lot. Just started taking Ester-C 24 hour immune Support, 3 tablets (1.5 grams) per day. Also recently switched to Enzymatic MB12. Seems to be some synergy between these two as I have been feeling very good for 5 days now since I started this. Yesterday I forgot to bring the MB12 to the office and had my normal crappy day despite the 3 tablets of the Ester-C. Today has been much better as I'm been nibbling on my MB12 throughout the day. I know Freddd metioned something about him taking a pretty good sized dose of MB12. I also noted in the ingredients is Rutin and Hesperidin. I did respond initially favorable to DAO enzyme so wondering if these might have had a histamine lowering effect and maybe that's why I'm feeling so good? Also wanted to note that I'm sleeping somewhat better, awakening with some energy and the dreams have been pleasant for a change.