I have read of the recent research around mast cell degradation and autism and the possibilities that this same action may be at play with CFS. I am going insane with itch and rolling migraines. I wonder if anyone has a view about whether the mast cell theories might hold true- based on response to products like Neuro protek or anything wiht natural luteolin? I am so desperate to stop the itch and migraine ( both of which may be mast cell based?) by taking these supplements. I have tried one capsule of Neuroprotek but got a massive head pain but am wondering if that was a reaction to quercitin in the the neuroprotek, rather than the leotolin. I may have to try something more pure like perilla oil? Anyone got any clues on any of this?