The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
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MAO-A Rs1137070

Discussion in 'Genetic Testing and SNPs' started by Peyt, Dec 23, 2015.

  1. Peyt

    Peyt Senior Member

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    Hi Everyone,
    I am +/+ for MAO-A Rs1137070
    Can someone explain to me how this gene may can effect my serotonin levels?
    I am getting contradictory info .... some sites says it's responsible to break down Serotonin so I would think that if I am +/+ then I must not be able to break down serotonin and thus have Serotonin syndrome (excess) . However, I see on Nutrahacker, the supplement recommended is Curcumin, and when I looked that supplement up, it says that it actually inhibit the enzymatic activity of MOA-A... So I don't get it, why would I want to take Curcumin to inhibit the activity?? Is this one of those genes that when impaired it would actually downgrades too much ??

    Can someone please explain to me how this works, and if Curcumin is the best supplement for it?
    Thanks
    Peyt
     
  2. ahmo

    ahmo Senior Member

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    Northcoast NSW, Australia
    I don't know the answer to your question. But I wrote about what seems to be a link between MAO and FMN form of B2, linked in my signature.
     
  3. Valentijn

    Valentijn Senior Member

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    It's a SNP, not a gene. But it is on a gene. And it probably doesn't effect serotonin levels at all. I'm not sure why anyone would mark it as being "+/+" or otherwise risky.
    Nutrahacker is an extremely poor source of information. I'd disregard anything they say.
     

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