Hey all I am about to start treating my Methylation Cycle. I am compound Heterozygous for MTHFR and Have several MTR/MTRR mutations. No COMT. I deal with anxiety and depression, although it has been pretty good lately, I am just hoping not to aggravate my depression/ anxiety when I start supplementing with Methylfolate/ B12. COMT won't be a problem so I am wondering if anyone has any information on the MAO A mutation. I have not found much on the MAO A mutation most stuff I can find on MAO deals with the "Warrior Gene." Does anyone have any experience with MAO and Methylation or have any information/research on the subject? Is MAO even a problem when treating Methylation or is it not much to worry about? Thanks a lot for any responses!