Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Maintenance of Chronic Fatigue Syndrome (CFS) in Young CFS Patients Is Associated with the 5-HTTLPR

Discussion in 'Latest ME/CFS Research' started by MEDad, Oct 18, 2015.

  1. MEDad

    MEDad

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    For those who think all is just well in Norway, think again. Certain people will always find (invent) a BPS explanation no matter what the findings are.

    Here they have a genetic variation correlating to CFS prognosis. As the the faithful members of the "church of BPS" they are, they couple their genetic findings to mental health, and argue that therefore mental health is a maintaining factor of CFS! These guys are supposed to be the "experts in Norway" apart from Fluge &Mella.

    http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140883

     
  2. Snow Leopard

    Snow Leopard Hibernating

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  3. msf

    msf Senior Member

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    Ah, the neuroticism that is a famous component of neurasthenia!

    Morons.
     
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  4. SOC

    SOC

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    And of course we don't know what their patient cohort really was, so it's not even clear whether the 26% of the people with the genotype have simple chronic fatigue or the neuroimmune illness ME/CFS.
     
  5. alex3619

    alex3619 Senior Member

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    Quite. I suspect that simplistic diagnostic criteria quite frequently confuse depression with CFS and vice versa, and does not address the core symptom of ME. So if they are not careful they will wind up with a large part of the cohort being depression.

    Please note the first link is to the full paper. If I have the energy I might read it.
     
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  6. Sidereal

    Sidereal Senior Member

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    As far as I remember from the many papers churned out by this psychobabble group in Norway, they have made up their own case definition for paediatric CFS (three months of fatigue, that's it).
     
  7. Sidereal

    Sidereal Senior Member

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  8. Sidereal

    Sidereal Senior Member

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    These two possibilities could help explain why some here keel over from serotonergic drugs and supplements while others benefit.
     
  9. Snow Leopard

    Snow Leopard Hibernating

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    Or this association occurred due to chance like so many other similar small scale studies of genetics of this nature.
     
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  10. MEDad

    MEDad

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    Yes they insist on using what they call "a broad case definition":

     
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  11. Sidereal

    Sidereal Senior Member

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    Well, this study didn't investigate serotonergic meds so there is no "association". This is just my personal speculation based on the biological mechanisms outlined and the range of reactions you see to these meds in the population at large.
     
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