The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Lyme in the tropics

Discussion in 'Lyme Disease and Co-Infections' started by msf, Aug 27, 2015.

  1. msf

    msf Senior Member

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  2. msf

    msf Senior Member

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    It´s also quite alarming, but not that surprising, to see how insensitive the WB was when compared with IF and PCR.
     
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  3. Thinktank

    Thinktank Senior Member

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    Europe + Asia
    There have been some cases of borreliosis in Thailand and other countries in the South East Asian region.
    China is quite hands on when dealing with stuff like this so i expect to see some interesting research and/or treatments coming from them in the next couple of years, especially with TCM.
     
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  4. duncan

    duncan Senior Member

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    Can't you almost hear the chanting chorus of "False Positives" flowing from the IDSA towers?

    I fear that chant of false positives may be a recurring theme in the new Guidelines. It's going to be increasingly difficult to deny the surging number of individuals that test positive -- pre- and post-treatment -- even with the outrageously high thresholds often currently set.

    I think a possible stance might be, "If you test negative, you can feel confident you don't have Lyme. If you test positive, measure against the backdrop of a specific symptom set (reduced to five or so), limited geography (what's the probability that YOUR neighborhood has Bb), etc, and maybe re-test in a bit, depending."

    A real conundrum these folks may have, imo, is explaining away, comfortably, the numbers of people who test positive post-treatment. They won't be able to keep to the party line that some folks will just keep snaring positives. Most meaningful studies demonstrate titers decline after treatment. The incidences where that isn't the case are only going to mount.

    It would seem China couldn't care less about the IDSA scriptures, thank goodness.
     
    Last edited: Aug 27, 2015
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  5. msf

    msf Senior Member

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    When I PMed ´Thailand borreliosis,´it came up with this, presumably because Maes is based there now:

    http://www.ncbi.nlm.nih.gov/pubmed/26081141

    No news to us, but it´s good that they are spreading the word.
     
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