Sorry, but I'm new here, and couldn't figure out quite where to put this question, so I'll ask it in the "General Forum". Can anyone tell me how it is determined whether you've had Lyme Disease or not? I know, it sounds like a stupid question, and may be, but I'm confused. Some things I read say that if any test comes back with a positive number, of ANY degree, then you've built Lyme antibodies, meaning you were infected at some point. Other sites suggest that the "titer" or number has to be above a certain level to be considered as positive. I guess my question comes from the little bits and snippets I've heard suggesting that "low-level" long-term infections with Lyme being one of the diseases, can be a factor in development of ME/CFS. Any help by pointing me to authoritative publications would be very appreciated, or if you have personal experience, I'd love to hear about that, too. Thanks!