The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
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Lyme Disease--Alzheimer's: Correlation

Discussion in 'Lyme Disease and Co-Infections' started by Lillybelle, Jul 14, 2014.

  1. Lillybelle

    Lillybelle Senior Member

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    Note: this thread is split off from the thread: CFS is a metabolic condition! which is here.

    A Lack of Correlation between the Incidence of Lyme Disease and Deaths due to Alzheimer's Disease.
    O'Day DH1, Catalano A2.
    Author information
    Abstract

    Reports that Lyme disease (LD) causes Alzheimer's disease (AD) have appeared in academic journals and online. If the biological agent Borrelia burgdorferi that causes LD also causes AD, then areas with the highest levels of LD should have significantly higher numbers of deaths due to AD compared to low LD areas. Here we show there is no statistically significant correlation between the incidence of LD and deaths due to AD in the US. Furthermore, the 13 states with the highest deaths due to AD were statistically different (p < 0.0001) from those with high LD incidence.

     
    Last edited by a moderator: Jul 26, 2014
  2. Lillybelle

    Lillybelle Senior Member

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    @MeSci Thanks for the pickup. Thought I hit the reply button to @GcMAF Australia
    @GcMAF Australia comment:
    "It is now being found that Borrelia - Lyme Disease is found in most Alzheimer's brains."
    I certainly would be following up on the possibilty of Lyme infection.
    -----------------------------------------------------------------------------------------------------------------------------------------
    A Lack of Correlation between the Incidence of Lyme Disease and Deaths due to Alzheimer's Disease.
    O'Day DH1, Catalano A2.
    Author information
    Abstract
    Reports that Lyme disease (LD) causes Alzheimer's disease (AD) have appeared in academic journals and online. If the biological agent Borrelia burgdorferi that causes LD also causes AD, then areas with the highest levels of LD should have significantly higher numbers of deaths due to AD compared to low LD areas. Here we show there is no statistically significant correlation between the incidence of LD and deaths due to AD in the US. Furthermore, the 13 states with the highest deaths due to AD were statistically different (p < 0.0001) from those with high LD incidence.
     
  3. Little Bluestem

    Little Bluestem Senescent on the Illinois Prairie ❀❤✿Ƹ̵̡Ӝ̵̨̄Ʒ✿❤❀

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    Maybe that is because Alzheimer's is not highly fatal. Most people who have it die of something else first. I would be more interested in whether there is a correlation between the incidence of Lyme Disease and the incidence of Alzheimer's Disease.
     
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  4. GcMAF Australia

    GcMAF Australia Senior Member

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    There is a major problem with the logic of this paper.

    Here are some links to Lyme and Alzheimers

    http://www.spirochaetalalzheimersassociation.org/intro.html

    http://www.miklossy.ch/

    http://alzheimerborreliosis.net/ (Alan McDonald)Cheers and regards
     
  5. GcMAF Australia

    GcMAF Australia Senior Member

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    I have seen some of the work on Lyme and Alzheimer's
    It is very convincing. see my previous post.
    Regards
     
    Little Bluestem likes this.
  6. Lillybelle

    Lillybelle Senior Member

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    Hi @GcMAF Australia I've checked for Alan Mcdonald on PubMed and it returns an error under his name.
    http://www.ncbi.nlm.nih.gov/pubmed?term=MacDonald AB[Author]&cauthor=true&cauthor_uid=16675154

    The articles Alan Macdonald links to on Google Scholar are not Alzheimers related.
    http://scholar.google.co.uk/scholar?start=0&q=ab macdonald&hl=en&as_sdt=0,5

    Also the study I quoted above was a quantitative and statistical analysis of the incidence of human Lyme Disease and human Alzheimers disease across the US.
    A further analysis is here: http://medicalxpress.com/news/2014-07-link-lyme-alzheimer-diseases.html
    warning of the danger of associating the two. Alzheimers is fatal, whilst Lyme disease is treatable.
    The United States is the only source to report location-specific data on the two diseases, but O'Day says that the findings are equally relevant in Canada. "While such complete data does not exist in Canada to make equivalent comparisons, there are no valid reasons this conclusion would not hold here as well as for any other country world-wide."

    "Because of this growing impact Alzheimer's disease will have in Canada and world-wide, we need to understand the true factors that underlie the disease," said O'Day. "We need to quickly rule out concerns, like Lyme disease, that unnecessarily cause widespread fear and interfere with attempts to fully understand the causes of Alzheimer's disease."

    The research was published in the August 2014 issue of the Journal of Alzheimer's Disease.

    It appears Alan Macdonald's research investigates Lyme disease in animals not humans. But I havent done a comprehensive review of all his published research.
    Cheers
     
    Last edited: Jul 19, 2014
  7. Lillybelle

    Lillybelle Senior Member

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    Alzheimers is the 6th Leading Cause of Death in the US and it is absolutely fatal.
    http://www.alz.org/alzheimers_disease_facts_and_figures.asp
     
    Last edited: Jul 19, 2014
  8. GcMAF Australia

    GcMAF Australia Senior Member

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    @Lillybelle
    The lyme doctors are finding large gaps in the canadian paper.
    The author of the paperis not an authority on Lyme.
    here is the list of Macdonalds papers on Pubmed.
    http://www.ncbi.nlm.nih.gov/pubmed/16675154

    I dont know why your link is not working
    http://www.ncbi.nlm.nih.gov/pubmed?term=MacDonald AB[Author]&cauthor=true&cauthor_uid=23479042
    For more info-
    http://alzheimerborreliosis.net/research/

    another person has published
    http://www.ncbi.nlm.nih.gov/pubmed/23346260
    and
    http://www.ncbi.nlm.nih.gov/pubmed/21816039

    Professor Judith Miklossy presented evidence at the sydney tick conference

    http://www.lymedisease.org.au/wp-content/uploads/2010/11/TBDConferenceNotesProfJMiklossy.pdf

    Who said Lyme is treatable??
    I know of many Australians who have died of Lyme, some commit suicide.
    The Lyme proficent doctors know about these things, they have many great problems treating Lyme Disease
    Regards
    Best regards
     
    Last edited: Jul 20, 2014
  9. knackers323

    knackers323 Senior Member

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    Hi do you know where I can find any info on those that have died or suicided due to lyme? Thanks
     
  10. GcMAF Australia

    GcMAF Australia Senior Member

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    Try Karen smith at this site
    http://www.lymeaustralia.com/
    Red Shoe day was started by Karen to commemorate those who were unfortunate to get proper treatment
     
  11. GcMAF Australia

    GcMAF Australia Senior Member

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    The statistical analysis is highly flawed as stated by Lyme doctors.

    Legal action is being taken against the US authorities because of behaviour which many have described as bordering on fraudulent.
    legal action is being undertaken in Australia against authorities,.
    The Canadian government has been warned that they face legal action.
    The Australian government has been warned that they face legal action.
    The web sites on Lyme in australia provide some information on the difficulties Australians face with diagnosis and treatment.
    The Australian Facebook sites have maybe 1000 people not treated properly.
    The US sites have just as many sufferers not being cured.
    Regards
     
  12. IreneF

    IreneF Senior Member

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    Who, exactly, is taking legal action, and against which authorities in the US? In which court? Can you refer us to a filing (so-and-so v. someone-else)?
     
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  13. GcMAF Australia

    GcMAF Australia Senior Member

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    1.https://www.facebook.com/permalink.php?story_fbid=10152147330264817&id=120608014816
    Glibowski vs. Us office of personnel mgmt., 09-cv-1039mca (us district court, district of new mexico)

    2. Occupy USDOJ http://www.actionlyme.org/

    3.see
    http://www.healingwell.com/community/default.aspx?f=30&m=2787075

    I shall check on others
    The Lyme doctors are trying something as well
    The CDC is regarded as being unethical, possibly negligent and legally liable
    Regards
     
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  14. Little Bluestem

    Little Bluestem Senescent on the Illinois Prairie ❀❤✿Ƹ̵̡Ӝ̵̨̄Ʒ✿❤❀

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    I did not say that Alzheimer’s Disease is not fatal, I said that it is not highly fatal. My guess is that there are a significant number of people who die of other causes, but also have Alzheimer’s. That is why I think incidence would be more relevant than death.
     
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  15. GcMAF Australia

    GcMAF Australia Senior Member

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    Dr MacDonald is finding evidence for Lyme in at least 90% of Alzheimers
     
  16. GcMAF Australia

    GcMAF Australia Senior Member

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  17. GcMAF Australia

    GcMAF Australia Senior Member

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    If late stage untreated Lyme represents say only 25% of today’s chronic illnesses it still presents a substantial threat to existing revenue streams. It is blatantly obvious that what has been put in place has been done so to deny the chronic or late stage Lyme epidemic.

    Comparison of Lyme Disease Prevalence and Disease Reporting in an Endemic Area
    http://article.sapub.org/10.5923.j.microbiology.20130306.11.html#Sec5

    Journal of Microbiology Research

    doi:10.5923/j.microbiology.20130306.11

    Holly AhernBiology Department, State University of New York at Adirondack, Queensbury, NY, 12804, USA

    In this study 16% of respondents experienced cardiac, rheumatologic, or neurological symptoms consistent with late-stage Lyme disease. Comparing late-stage Lyme symptoms to the general population was a brilliant idea because we believe the vast majority of Lyme patients are already in the healthcare system being treated for everything elsebutLyme.

    Our current 2-tier Lyme disease analysis has a sensitivity of 59%which is not much better than a coin toss. Faulty diagnostic tests have led to the disability of tens of thousands of Lyme patients through misdiagnosis and delayed treatment. Late stage Lyme disease does not respond well to short courses of antibiotics leaving these patients with the dilemma and financial burden of finding a way to treat beyond the IDSA’s one-size-fits-all treatment guideline. It is time to recognize that serodiagnostics for Lyme disease is inherently flawed and should be scrapped for testing capable of measuring treatment failure or success in all stages of disease. (Unless of course it is necessary to hide evidence of persistent infection for some undisclosed purpose.)

    Author-disambiguation algorithms and bibliometric analysis platforms are not a substitute for accurate/reliable diagnostic tests.
     
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  18. Lillybelle

    Lillybelle Senior Member

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    I think as the 6th leading CAUSE of Death, Alzheimers is extremely prevalent and highly fatal. And yes it is the actual Alzheimers that kills people.
    http://www.livestrong.com/article/140863-how-does-alzheimers-eventually-kill-you/

    "While people with AD may die of other unrelated conditions, such as a heart attack, death from AD typically results from complications related to loss of critical brain functions." According to the Centers for Disease Control and Prevention, Alzheimer disease is the sixth most common cause of death in the United States. AD is a progressive degeneration of the gray matter of the brain, which controls thinking, memory, movement and sensation.
     
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  19. Lillybelle

    Lillybelle Senior Member

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    Where exactly has the Australian Govt been warned about legal action on Lyme?
    And whilst there is a call in the US for a congressional investigation. Legal action has not been taken yet.

    Sorry this link
    http://www.actionlyme.org/ talking about "govt whoring for its corporate pimps" does not convince me of anything. There is no evidence I can see there.

    I believe you and many others have valid and real concerns about the prevalence and importance of Lyme disease. But using extreme statements such as "Lyme disease causes Alzheimers in 90% of patients". Is not helpful to the plight of Lyme or Alzheimers sufferers when it has not been proven in replicated and controlled studies.
     
  20. GcMAF Australia

    GcMAF Australia Senior Member

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    It is hard to get funding for any Lyme studies.
    the ignoring of lyme disease in australia is not helpful either
     
    Lillybelle likes this.

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