Do you know your copper and zinc status? I'm asking because what you're going through sounds very similar to what I went through a few years ago when I got put on methyl vitamins. A true overmethylator will be high in copper. Zinc may look like it is normal, but the ratio will be off in favor of too much copper, so more zinc will be needed. There are other things besides food and niacin that raise histamine levels. Just search things that raise histamine levels. Vitamin C is a natural antihistamine and can really mess up an overmethylator. I cannot add a link, but there is a website that has a simple explanation. Search 2.3 histapenia/histadelia. It should bring up an orthomolecular treatment website. Do you fit in either of these categories? Also look at 2.4 pyroluria on the same page.
First of all, thank you for your answer.
Before my over methylation induced state, Zinc and Copper were well balanced. I have some symptoms of histapenia. Before I induced this state of overmethylation, my main problem were: low motivation, low libido and hypoglicemia attacks during the night. But I was very happy, my life was good.
I just used methyl stuff because the first time I used mfolate and mb12, I had an incredible good reaction. But I forgot I also used 100mg niacin that time, and I was giving all merits to methyl folate and methyl b12. I haven't any MTHFR mutation, only MTRR, but before this experiment mb12 did nothing good to me. So, niacin was the big guy who had help. Ok, also folate and b12 a little bit because they have some part on histamines.
For the gut, you can try digestive enzymes for overall digestion, either magnesium or fiber can help with constipation.
For the hydroxy, depending on if it's kind of a toxic reaction (in other words, not overmethylation), you can try some baking soda water. (follow the directions on the box for the standard dose for indigestion). Sip slowly. This helps neutralize it.
If it's more like overmethylation, the other thing Ben Lynch said to try was curcurmin.
Stop experimenting with methyl supplements!!!! (B12, folate, TMG, etc) I don't understand why you would take something again that made you feel bad before.
Please consult with a methylation doctor - there are several who work by phone and email and will work with people in other countries.
There are links to two practitioner lists, see my signature link.
I'll try fiber. I'm not taking any methyl supplement.
I'm just taking small doses of hydroxy now, don't know if it can cause some harm, but maybe no.
I'll attack every hypothesis. I induced a folate trap before my over methylation state, and ammonia build up is also a hypothesis (have 2 +/- cbs), so:
Eating yucca root (yea eat, here in my country is very easy to find), use hydrox b12 and also small doses of b6 to aid excitotoxity and pancreas.
-> I stopped taking niacin, and my blood glucose is increasing a lot. Niacin increases insulin production (lowers my BG, I measured), but it causes insulin insensibility. Need to take a break of at least 20days to let my system calm down.
ps: I'm dealing with hyperventilation and gut contractions 24/7. Pretty sure dealing with excitotocity that can be harmful with time.
