Julie Rehmeyer's 'Through the Shadowlands'
Writer Never Give Up talks about Julie Rehmeyer's new book "Through the Shadowlands: A Science Writer's Odyssey into an Illness Science Doesn't Understand" and shares an interview with Julie ...
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Lowering IGF-1 and raising autophage activity: good for ME, or not?

Discussion in 'General Treatment' started by Sasha, Jan 23, 2013.

  1. Sasha

    Sasha Fine, thank you

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    In another thread I've been discussing whether intermittent fasting would be good for PWME. It's supposed to reduce levels of IGF-1 and increase autophage activity.

    Would these be good things in PWME, or not? Reducing levels of IGF-1 is supposed to reduce inflammation and your risk of cancer, among other things and since ME seems to involve chronic inflammation I wondered about this.
     
  2. Crux

    Crux Senior Member

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    Hi Sasha;

    Elevated IGF-1 has been a big worry for me these past years, especially this one past. Mine steadily climbed to 166 pts. above highest normal for my age/gender.

    I just received my most recent IGF-1 levels, and I'm relieved to report that they've come down 165pts. ( still too high, but much much better.)

    I attribute this to my zinc supplementation this past 10mnths. Zinc has regulatory properties. Typically, with zinc deficiency, there is low growth hormone, and low IGF-1. I took a chance, and hoped it would help regulate my elevated levels. ( I average between 7.5-15 mgs. daily in supps.)

    I still need to continue to lower my IGF-1, by additional means, but I'm not so freaked out about it.
    I'm preparing to start supplementing with EGCG, Curcumin, and Resveratrol. They've demonstrated IGF lowering properties, in a few studies.

    Thanks for the thread!
     
    Sasha likes this.
  3. Emootje

    Emootje Senior Member

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