Hi everyone, since av's my cfs has improved greatly, but over the last 2 months have had lower back problems as well as achey legs when i sleep which i have had since cfs, the type that feels like shin splints or growing pains etc and wakes me at early hours of the morning. I know alot of people with cfs get this. It is unrelated to my lower back problem and is not sciatica. I have been taking lyrica for this and it has helped alot. I do occassinally use seroquel for insomnia which i know worsens restless leg syndrome but normally with lyrica its good, if i dont take lyrica and just seroquel on its own, i get stiff all over. Ok, what i want to do is try to lose weight to help my lower back pain. Normally when i drop my carbs very low and keep strict i lose weight, this has been the only way i can drop weight. But my weight hasnt budged, if anything has gone up abit, which i think is due to lyrica, which inturn has stopped working for my leg pain. viscious circle. I have been looking into a couple of meds to ask my doc about and want anyones experience with them. I know dopamine agonist are sometimes used but after reading about them, im not to found of them, i think they might worsen my sleep. I have looked into topamax and gabitril, both seem like they could help. Im leaning towards gabitril has it has a shorter half life then topamax and have heard topamax can make you very groggy the next day, which Im not keen on. Gabatril also could help me sleep and both could help with leg pain as well as lower back pain. Gabitril from what i have read is weight neutral where as topamax can help you lose. Which do i go for , topamax which can aid my weight loss, but feel groggy during the day or gabitril which is weight neutral and minimal hangover. Both have other good qualities that can help other conditions too. Im sure doc will let me try one and if not suitable try the other. I want to guess right first time. Cheers!!!