• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

Low Sulfite--high uric acid --need help

Messages
30
I have lot of ongoing symptoms and since its very hard for me to lose weight.
http://www.canarys-eye-view.org/metabolic_basis/sulfur_metabolism/homocysteine.html
I am on 600kcal diet from long time. and recently I did all my test where it reveal that I am low in iron, nitrogen and DHEA but my uric acid is on normal high side.

http://forums.phoenixrising.me/index.php?threads/heres-the-cbs-sulfate-sufite-answer.15113/

My serum Zinc is on higher normal side but its more toward bio unavailable. My symptoms are related to overmethylation (low serum histamine) as I am not sure of pyrrole as my test didn’t show up this disorder. I tested my urine sulfite and its 25/1000 by using these test strips.

http://www.amazon.com/gp/product/B0089PPEGI/ref=oh_details_o00_s00_i00?ie=UTF8&psc=1

The Defect(s) in my Sulfur Metabolism

http://www.canarys-eye-view.org/metabolic_basis/sulfur_metabolism/sulfur-defect.html


I can easily recall my dream and it’s more toward excessive dreaming. I am confused for one thing that even my serum B vitamins are in good range but when reviewing them at cellular level they are deficient.

My problem is more related to cellular membrane problem. Due to gene defect, as I am low in cellular b12 and serotonin as well.

http://mthfr.net/forums/topic/low-sulfur-and-hormones-dr-ben-lynch/


Even my histamine was in normal low level at serum but at cellular level it become extremely low. These days’ my symptoms are given as follow.
1. Extremely tired
2. Feeling cold
3. Water retention and unable to lose weight (my water intake is one glass a day from long time) I feel full when consume 3 cups of water or food together.

I noticed my cellular Arginine was in normal high range and I have problem breaking down it further as may be related to NO/NOO syntheses or b3 deficiency. My cellular potassium is very low so you think GABA diet or Blood Brain barrier diet will improve it.

At cellular level I am going toward pyrrole disorder? My serum homocysteine is in ideal range but at cellular level it’s very low. May be its relate to SAM that isn't recycled; where does that go? It goes to make cysteine, glutathione, taurine, and sulfates. That pathway is very dependent on vitamin B6 coenzyme. I have sulfur hormones deficiency including serum iron and Ferittin are very low with DHEA and low nitic oxide, low homocysteine and urine sulfite range are 25/1000.

Serum hormones blood------Urine hormones compare results – blood capillary hormones
1. Thyroid high ----- Blood spot-low

2. Carnitine low ------ Carnitine high

3. Copper - high ------ Copper (hair analysis low)

4. B 12- high ------ B 12 low

5. Zinc high-serum ------- Zinc (hair normal low)

6. Iron middle range -------- Ferritin – low serum plus low hair

7. Calcium serum ok --------- Calcium hair high------Calcium urine low side
Fact never took Cal my entire life + Mag

8. Folic Acid - low--------- Folic Acid RBC normal low

9. Magnesium ok ---------- Magnesium RBC normal low
10. Potassium OK --------- Potassium very low-Hair
11. Cortisol toward high -- Cortisol urine ok

12. Anti diuretic hormone high

13. Aldosterone low

14. Spo2 99%
15. Fasting sugar 99 on 40 g carb diet
16. TH2 dominance

Urine Ph usually 5.5 to 6
In morning it remains same so it relate to glycolisis
I read that Sodium/potassium pumps located in the cell membrane. Potassium relates to cell membrane function and proper enzyme activity. Low potassium within the cell may cause abnormalities in many biologic processes; including the cell volume, acid-base balance, production of RNA and Glycogen, and dramatically reduces the ability of the cells to support muscle contractions.

http://americannutritionassociation.org/newsletter/autism-where-are-we-what-can-be-done

http://forums.phoenixrising.me/inde...onors-same-tmg-any-others-ie-dmg.14608/page-2

I started Dr Amy Yasko protocol but for CBS problem as everyone need to avoid sulfur and it makes my symptoms of hyperventilation worse.

How can your protocol help me and why my urine sulfite level are 25/1000 range.
How to improve low PST pathway and I am looking forward for help.
thanks,
 
Messages
18
Location
Texas
I have lot of ongoing symptoms and since its very hard for me to lose weight.
http://www.canarys-eye-view.org/metabolic_basis/sulfur_metabolism/homocysteine.html
I am on 600kcal diet from long time. and recently I did all my test where it reveal that I am low in iron, nitrogen and DHEA but my uric acid is on normal high side.

http://forums.phoenixrising.me/index.php?threads/heres-the-cbs-sulfate-sufite-answer.15113/

My serum Zinc is on higher normal side but its more toward bio unavailable. My symptoms are related to overmethylation (low serum histamine) as I am not sure of pyrrole as my test didn’t show up this disorder. I tested my urine sulfite and its 25/1000 by using these test strips.

http://www.amazon.com/gp/product/B0089PPEGI/ref=oh_details_o00_s00_i00?ie=UTF8&psc=1

The Defect(s) in my Sulfur Metabolism

http://www.canarys-eye-view.org/metabolic_basis/sulfur_metabolism/sulfur-defect.html


I can easily recall my dream and it’s more toward excessive dreaming. I am confused for one thing that even my serum B vitamins are in good range but when reviewing them at cellular level they are deficient.

My problem is more related to cellular membrane problem. Due to gene defect, as I am low in cellular b12 and serotonin as well.

http://mthfr.net/forums/topic/low-sulfur-and-hormones-dr-ben-lynch/


Even my histamine was in normal low level at serum but at cellular level it become extremely low. These days’ my symptoms are given as follow.
1. Extremely tired
2. Feeling cold
3. Water retention and unable to lose weight (my water intake is one glass a day from long time) I feel full when consume 3 cups of water or food together.

I noticed my cellular Arginine was in normal high range and I have problem breaking down it further as may be related to NO/NOO syntheses or b3 deficiency. My cellular potassium is very low so you think GABA diet or Blood Brain barrier diet will improve it.

At cellular level I am going toward pyrrole disorder? My serum homocysteine is in ideal range but at cellular level it’s very low. May be its relate to SAM that isn't recycled; where does that go? It goes to make cysteine, glutathione, taurine, and sulfates. That pathway is very dependent on vitamin B6 coenzyme. I have sulfur hormones deficiency including serum iron and Ferittin are very low with DHEA and low nitic oxide, low homocysteine and urine sulfite range are 25/1000.

Serum hormones blood------Urine hormones compare results – blood capillary hormones
1. Thyroid high ----- Blood spot-low

2. Carnitine low ------ Carnitine high

3. Copper - high ------ Copper (hair analysis low)

4. B 12- high ------ B 12 low

5. Zinc high-serum ------- Zinc (hair normal low)

6. Iron middle range -------- Ferritin – low serum plus low hair

7. Calcium serum ok --------- Calcium hair high------Calcium urine low side
Fact never took Cal my entire life + Mag

8. Folic Acid - low--------- Folic Acid RBC normal low

9. Magnesium ok ---------- Magnesium RBC normal low
10. Potassium OK --------- Potassium very low-Hair
11. Cortisol toward high -- Cortisol urine ok

12. Anti diuretic hormone high

13. Aldosterone low

14. Spo2 99%
15. Fasting sugar 99 on 40 g carb diet
16. TH2 dominance

Urine Ph usually 5.5 to 6
In morning it remains same so it relate to glycolisis
I read that Sodium/potassium pumps located in the cell membrane. Potassium relates to cell membrane function and proper enzyme activity. Low potassium within the cell may cause abnormalities in many biologic processes; including the cell volume, acid-base balance, production of RNA and Glycogen, and dramatically reduces the ability of the cells to support muscle contractions.

http://americannutritionassociation.org/newsletter/autism-where-are-we-what-can-be-done

http://forums.phoenixrising.me/inde...onors-same-tmg-any-others-ie-dmg.14608/page-2

I started Dr Amy Yasko protocol but for CBS problem as everyone need to avoid sulfur and it makes my symptoms of hyperventilation worse.

How can your protocol help me and why my urine sulfite level are 25/1000 range.
How to improve low PST pathway and I am looking forward for help.
thanks,


I'm going through a lot of what you are and have done a TON of research I think I have some awnsers for you but it's late I will get on that this week in the meantime if you could post you snp's that would be helpful.
 
Messages
30
Thank you for replying back to me and please find my SNP result from Dr Yasko.
Please review my results:

COMT ———–V158M ———-+/- ———Hetero
COMT ——H62H——- +/- ———-Hetero
COMT ———61 ——– -/- ——-G

VDR ———–Taq—— tt ———-C
VDR ——–Fok———- FF———- C
MAO A ———–R297R————— +/+ ———–T
ACAT———— 1-02———— +/- ——–Hetero
MTHFR———– C677T ————- -/- ——–C
MTHFR———– 3 ———– -/- ———–C
MTHFR———- A1298C———— -/- ——–A

MTR——— A2756G————– +/+ ——–G
MTRR———- A66G———– +/+ ——-G

MTRR———– H595Y———— -/- ———C
MTRR——– K350A———— -/- ——–A
MTRR———- R415T———- -/- ———C
MTRR ————-S257T ———– -/- ——–T
MTRR ————–11————- -/- ———G
BHMT————- 1———– -/- ————– A

BHMT————– 2 +/- ———–Hetero
BHMT ————–4 ————-+/- ———Hetero
BHMT ————-8————– +/- ———Hetero

AHCY————- 1 ———-+/- ——- Hetero
AHCY———- 2 ———+/- ———-Hetero
AHCY ———19————- +/- ———Hetero
CBS ———C699T————- +/- ————Hetero
CBS ———-A360A +/- Hetero

CBS ————N212N ———– -/- ——-C
SUOX ————S370S ———— -/- ———-No Support Needed
SHMT ————C1420T————- -/- ————G
NOS ————D298E -/- G
This year I performed Genova complete hormone with Genova Rythum plus tests as well with UEE from Doctor Data lab. I am keeping my finger crossed and waiting for your reply.
Take Care,
 
Messages
18
Location
Texas
Thank you for replying back to me and please find my SNP result from Dr Yasko.
Please review my results:

COMT ———–V158M ———-+/- ———Hetero
COMT ——H62H——- +/- ———-Hetero
COMT ———61 ——– -/- ——-G

VDR ———–Taq—— tt ———-C
VDR ——–Fok———- FF———- C
MAO A ———–R297R————— +/+ ———–T
ACAT———— 1-02———— +/- ——–Hetero
MTHFR———– C677T ————- -/- ——–C
MTHFR———– 3 ———– -/- ———–C
MTHFR———- A1298C———— -/- ——–A

MTR——— A2756G————– +/+ ——–G
MTRR———- A66G———– +/+ ——-G

MTRR———– H595Y———— -/- ———C
MTRR——– K350A———— -/- ——–A
MTRR———- R415T———- -/- ———C
MTRR ————-S257T ———– -/- ——–T
MTRR ————–11————- -/- ———G
BHMT————- 1———– -/- ————– A

BHMT————– 2 +/- ———–Hetero
BHMT ————–4 ————-+/- ———Hetero
BHMT ————-8————– +/- ———Hetero

AHCY————- 1 ———-+/- ——- Hetero
AHCY———- 2 ———+/- ———-Hetero
AHCY ———19————- +/- ———Hetero
CBS ———C699T————- +/- ————Hetero
CBS ———-A360A +/- Hetero

CBS ————N212N ———– -/- ——-C
SUOX ————S370S ———— -/- ———-No Support Needed
SHMT ————C1420T————- -/- ————G
NOS ————D298E -/- G
This year I performed Genova complete hormone with Genova Rythum plus tests as well with UEE from Doctor Data lab. I am keeping my finger crossed and waiting for your reply.
Take Care,

Ok first off blood amino acids are a snapshot of the last 18 hrs. They do not accurately reflect what is going on long term eg your condition like urine does. Urine excretes what's in the tissue and is a more accurate reflection of what is going on amino acid wise in your body.

What exactly do you mean when you say your homocysteine is normal but low at a cellular level. How did you test that?

When you say sulfite 25/1000 are you using strips to test this? And it's sulfite not sulfate?

Also a hair test with high anything reflects a deficiency. Your hair is nothing but a connective tissue when your body is low in a mineral or deficient it stores as much as it can in the tissue eg hair. That's why many time a urine mineral test will show for example low zinc but it will be high in hair, this is a deficiency.

How are your b6, b12, and folate levels and what tests have you done to test them?

I also have low nitric oxide and am cold hand and feet all the time. How did you or they test / or come to this conclusion? I did the saliva strip test. Along with frequency testing and 3d intrafulid testing as well as the obvious physical symptoms.