7 weeks into LDN so far and I am excited to continue taking it and hope it will continue to help improving for another couple months. I was ~75% when starting to take it and have reached ~85% around this time. I was able to do a - albeit shortened to 35 minutes - kickboxing class today without getting any PEM besides minor transient congestion/oxygenation issues. Besides I can exercise moderately around 2-4 times per week for 30-45 minutes (in addition to the CVAC therapy). I still feel worst in the morning (around 10 am) and have residual moderate inflammatory pain and very mild respiration issues plus currently also fairly mild IBS/cramping and much reduced muscle twitching. I still get sweaty and twitchy right after taking the LDN (started with half and am on full 4.5 mg dose since week 3) and can feel temporarily increase in pains (mostly needles and pins) and it takes a while to fall asleep, but once asleep I sleep better than before and insomnia has been reduced. I had a period of increased gland swelling and tenderness around 3-4 weeks on LDN but ironically felt very energized then. It may not be a cure and I may need to continue for a few more months, but so far it seems to have been a small miracle.