garcia i agree with you as far as taking lose dose ldn and it not doing anything.i felt something happening at a 1/4 of 1 mg. i'm now up to 1 mg and my sleep has been much better,i wake up once then i'm out again. i have to say i really am feeling a difference.i'm up at 6am every morning with energy and i'm good til about 2pm.i have a wee nap then i'm good until 10.my brain fog has decreased which is a blessing for me i couldn't think straight.please understand i'm not 100% but i think the increase is at least 15 to 20%. dr klimas mentioned the imunovir would take about 4 months to notice a difference.that would be june. i will continue the ldn until i'm at optimal dose 4.5.and may stay on it forever because of the great things i've read regarding lymphoma. i haven't once doubted this drug,,i don't know why as i'm usually leary it's too good to be true.but so far so good.