Julie Rehmeyer's 'Through the Shadowlands'
Writer Never Give Up talks about Julie Rehmeyer's new book "Through the Shadowlands: A Science Writer's Odyssey into an Illness Science Doesn't Understand" and shares an interview with Julie ...
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Low Dose Dextromethorphan (cough syrup) looks promising. Has anyone tried it?

Discussion in 'Latest ME/CFS Research' started by BeautifulDay, Oct 11, 2017.

  1. MAOAr297r

    MAOAr297r Senior Member

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    Seattle
    Well said. As someone who has struggled with dp/dr and tried low does dxm I can confirm this. Thats also the reason I wasn't given ketamine for my depression even though I was eligible . dp/dr= no fun.
     
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  2. SueJohnPat

    SueJohnPat Sue

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    Medford NJ
    I have taken dxm for long periods of time for a chronic cough. It did nothing for the cough but I figured it might help due to its ketamine like properties. I did not notice any improvement.
     
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  3. Wishful

    Wishful Senior Member

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    Tried it (a couple of experiments of varying duration, recommended and lower dosage); did nothing for me.
     
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  4. debored13

    debored13 Senior Member

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    Vermont, school in Western MA
    I have done lots of ketamine since I initially got lyme, and before I had figured out that I probably had CFS.
    I think ketamine tended to give me great relief from a certain kind of agitated sensation in my head that was part of my illness. It's hard to explain but there are really specific sensations that i get that aren't pain but are part of being sick. Anyway ketamine would relieve this agitation similarly to gabapentin, which i was prescribed. The problem was at that point I still couldn't sleep without meds, and I felt nervous taking my sleeping meds after ketamine usage. This was kind of stupid because ketamine causes next to no respiratory depression. Anyway I'm curious to try ketamine and/or dxm now.

    For the past four months I've done basically no drugs at all, just because they wear me out and i'm already too tired.

    I will say this... the toxic aspects of having a hangover from a gabaergic drug are generally due to glutamate excitotoxicity, too much glutamate release causing overexcitation of neurons. I have been so, so , so much more sensitive to GABAergic hangovers since my initial Lyme diagnosis and probable CFS. I can't know that it's due to glutamate without a biopsy or something, but I can strongly suspect that that's what's going on. It has been a clear pattern. So I wonder if glutamate excess is part of CFS.

    Anyone else notice this?
     
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