I've been on atenolol for a couple years and it's helped some. I used to have to stay laying flat most of the time before atenolol. I can at least sit up now. I wish I could get rid of the POTS. I think it's my worst symptom. Is the adrenalin rush part of POTS or something different. I have to be so careful about any caffeine or any kind of stimulant or I fell so incedibly sick. I am so super sensitive to everything. Even to take atenolol I had to start with just a small piece of the pill and work up.