I am taking 1/4 tablet of Bystolic (5 mg.) every morning. The following symptoms have disappeared: chest pain heart palpitations inability to raise arms even momentarily inability to stand for short amount of time pre-syncope pounding heart shortness of breath P.O.T.S. episodes: upon standing a 20-30 pt. increase in heart rate, tachycardia then sharp decline in B.P., followed by the "must sit right now" feeling My husband says he's noticed a "tremendous" difference in my functioning. It's simply inexplicable --- the difference in CFS without P.O.T.S. I still have the other symptoms of CFS: weakness (energy envelop), cognitive dysfunction, sleep problems, mandatory rests, pain, etc. However, I'd say my functionality has gone up at least one point. :Retro smile::Retro smile: I hope this helps someone.