The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
Discuss the article on the Forums.

Low dopamine and eprinephrine levels?

Discussion in 'Hormones' started by hollasort, May 31, 2017.

  1. hollasort

    hollasort

    Messages:
    7
    Likes:
    1
    South Dakota, USA
    Hi All, I have been getting most of my Mayo blood work back this week and pretty much everything is normal-- aside from a slightly elevated CRP and a rather low dopamine and a very low epinephrine. Does anyone know if these low levels are related to ME/CFS?

    Thanks, Holly
     
  2. NotThisGuy

    NotThisGuy Senior Member

    Messages:
    214
    Likes:
    208
    Germany
    Yes, I figured that low dopamine and norepinephrine are one of my main issues. Not epinephrine though (Or whatever causes those low levels, For me its Lyme and heavy metals and probably a few other infections).

    Have a close look on the tyrosine pathway.
    Tyrosine needs Vitamin D, B1 and BH4 (among others) to convert to dopamine.
    Dopamine needs Vit C and copper to convert to norepinephrine.
    Norepinephrine needs cortisol and SAMe to convert to epinephrine.

    Increasing dopamine and norepinephrine doesn't heal me, but it makes the difference between beeing on activity level 1 or activity level 5.
     
  3. helios

    helios

    Messages:
    81
    Likes:
    32
    Brisbane
    Are they going to do anything about your dopamine?
    My guess is no if its just 'low'.
    what test did they do to measure it? I am guessing saliva as there is no blood test for it, well not where I live. I'm convinced I have low dopamine, but doctors don't give any credence to saliva tests so there is no test so they can just dismiss any patient's theories/research and push an ssri (with zero evidence its a serotonin issue :: sigh:: I actually managed recently to convince my doc to try me with low dose amisulpride. it has not been a revelation for my health, in terms of reducing brain fog and increasing motivation & desire, but it has given me really good dreams and boosted libido (in the morning only) and given me a slighter sense of calmness & well being & less depression.
     
    sb4 likes this.
  4. bertiedog

    bertiedog Senior Member

    Messages:
    970
    Likes:
    1,297
    South East England, UK
    You also need fully functioning enzymes but due to genetics you could have issues that are depleting these neurotransmitters. Environmental factors could add stop the be problem too and would need to be addressed.

    Pam
     
  5. bertiedog

    bertiedog Senior Member

    Messages:
    970
    Likes:
    1,297
    South East England, UK
    Just a thought, did you ever have an organic acid test done through a company like Genova because that will show the metabolites from the various neurotransmitters and might indicate where there are issues for you.

    Pam
     
  6. NotThisGuy

    NotThisGuy Senior Member

    Messages:
    214
    Likes:
    208
    Germany
    no I haven't done this test.
    I have to drink a lot of water and got polyuria. Also I have MCAS and can only tolerate 3 foods.
    Genova says both of this factors will influence the organic acid test. I fear the results might be worthless and money is wasted.
     
    bertiedog likes this.

See more popular forum discussions.

Share This Page