Hi All, I am encouraged with significant improvements on a low and slow version of the methylation protocol. It took six months to reach "saturation", but once I did, my improvements all happened virtually overnight. The areas of greatest improvement are as follows: perceived stress is gone, brain fog 50% better, fatigue 50 % better, neuropathy (leg pain) gone, insomnia 50% better, ability to multitask 50% better, socialization 50% better. The areas that have not yet improved significantly: muscle spasms and muscle weakness (ANY IDEAS?), intermittent brain inflammation, ability to self motivate physical exercise (I have been active and thin all of my life), and bloating/abdminal discomfort/yeast. I asked my doctor for a parasite test which will look for blastocystis hominis, in addition to other bad bugs. He think bh is a good likelihood. I know that I am dealing with a biofilm because my bloating issues always return if I start eating carbs, sugars, etc. or if I discontinue olive leaf or oil of oregano. BIG CONCERN: I woke the other night with a brain tremor, then numb tongue, then profuse sweating. Tongue continued to tingle for several days. I am concerned that this may have been some type of seizure..........or could I be detoxing metal from my brain. I am not doing any type of chelation since it seems so confusing, and I'm really not trying to move metals at this point. Could any of the below supplements have lead to this tremor? Have any of you experienced this? Although all of our experiences are different, I feel that you have a truckload of knowledge that I can use to inform my own decision making process. Happy holidays! therron Current Critical Supplements (I started with crumbs of each one 7 months ago, then worked up to these amounts). Mb12 1,000 mcg in am 500 mcg in pm Douglas B complex 1 capsule in am methylfolate 400 mcg in am (there is another 400 in B complex) 800 mcg in pm TMG 500 mg in am and 500 in pm p5p 15 mg in am 30 in pm I also take dibencozide, zinc, biotin, D3, omega 3 fish oil, ubiquenol, milk thistle, magnesium oil, betaine HCL, oregano oil, olive leaf My breakthrough came at 6 months after doubling my methylfolate, p5p, and TMG.