Phoenix Rising tells QMUL: release the PACE trial data
Mark Berry, Acting CEO of Phoenix Rising, presents the Board of Directors’ open letter to Queen Mary University of London (QMUL) urging them to release the PACE trial data, and hopes that other non-UK organisations will join British charities in the same request...
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Long-chain acylcarnitine deficiency in CFS. Potential involvement of altered carnitin

Discussion in 'Latest ME/CFS Research' started by Dolphin, Dec 31, 2010.

  1. TheMoonIsBlue

    TheMoonIsBlue Senior Member

    I was looking up what Carnitine supplements Thorne Research offers (they're one of my fav. brands) there were a few, but one thing caught my eye:

    Acetyl-L-Carnitine (Carnityl, brand name) "............Other studies have shown ALC may be of benefit for maintaining a positive mood in the elderly, possibly by partially inhibiting the activity of the hypothalamic-pituitary-adrenal axis and lowering chronically elevated cortisol levels (which become elevated during stressful situations).*

    This may be something to be aware of if a person has chronically LOW cortisol levels.

    On the other hand, another product they have which is just called L-Carnitine, it says nothing about lowering Cortisol levels.

    So does Acetyl-L-Carnitine act differently than just L-Carnitine in this way, affecting Cortisol?
  2. Dolphin

    Dolphin Senior Member

    FWIW, not sure I recall talk about carnitine and cortisol. That statement doesn't look very definite. Possibly best to look at scientific research if anyone has time.
    I don't have time to look through the PubMed results for cortisol carnitine.
    One I see is:
    but I only looked at two.
  3. alice1

    alice1 Senior Member

    glenp have you tried supplements plus.I have l-carnitine so I know we can get it here in Canada.
  4. glenp

    glenp "and this too shall pass"

    Vancouver Canada suburbs
    Thank you Chris - I am going to ask my doctor for a prescription rather then taking the undated product that am able to get here

    Just a reminder to everyone, there are various forms of carnitine- the one I and Chris mentioned is Acetyl-l-carnitine - now available as Chris mentioned with a prescription in Canada -

    Side effects
  5. omerbasket

    omerbasket Senior Member

    Sorry for bringing it up - but I wondered: How/Where can I buy a supplement that would include the ingredients that they found to be deficient in ME/CFS patients, like Oleyl-L-Carnitine and Linoleyl-L-Carnitine, as opposed to L-Carnitine and Acetyl-L-Carnitine, which, in their study, were not downregulated?

    If someone has an answer, I'd be glad to hear (or read...) it :D

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