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Lithium orotate, methylation and thyroid

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Beyond, Jul 12, 2013.

  1. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    It seems its reccomended for my gene mutations to take lithium, plus I have read it helps with sleep, mood and protects the brain from neurotoxins (very needed). But its a fact that lithium supresses thyroid function to some extent and I suspect some degree of thyroid problems. Anyone takes lithium per Yasko reccomendations having possible subclinical hypothyroidism or hashimoto´s?
     
  2. juniemarie

    juniemarie Senior Member

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    Hope someone has some input on this as I was considering taking lithium orotate but I cant afford to have anything slow down my thyroid.......I didn't know that about LO, where did you hear about that?
     
    Beyond likes this.
  3. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I am known as one very effective dataminer or Google hound. :D I found it in forums and clinical studies. Always desperate to find something for sleep so today decided to look for it and some people really get better sleep with lithium.
     
  4. Dreambirdie

    Dreambirdie work in progress

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    Interesting. I have tried lithium arginate and felt a bit over-stimulated from it.
    I wonder if there would be a difference with the lithium orotate?
     
  5. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I attracted you to this thread with telepathic strings, Dreambirdie ;) As I was just writing in that thread of yours! :rofl:

    I wonder too. If you try report back.
     
  6. Dreambirdie

    Dreambirdie work in progress

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    hehehe. :) Well here I am, but you didn't answer my question regarding lithium orotate vs lithium arginate... and I am not up for joining another forum. So let me know what you find out. thanks.
     
  7. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I am not an expert in lithium, sadly, but orotate its the one most reccomended and the one I would try. I think there can be a difference. About the link, I forgot you guys cannot go inside. It has some insights on lithium and thyroid/iodine.

    Its the forum of Yasko. The thread says basically that Iodine and Lithium are antagonic, if taking Lithium one should take Iodine which minimizes its antithyroid effecs and one should be taken at mornings and other night because lithium disrupts iodine metabolism.
     
  8. Dreambirdie

    Dreambirdie work in progress

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    Taking iodine was the 2nd worse thing I ever did. The first worst was hydrocortisone. Never again.

    So maybe lithium is not the best thing for me.
     
  9. taniaaust1

    taniaaust1

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    I take lithium orotate due to showing very low abnormal level on a hair test and have a family history of hypothyriodism (3? family members), so thanks greatly for your info. Maybe my low lithium level could even be protective then?

    Ive been wondering if there is a polymorphism or something which can cause low lithium?
    ..........

    Beyond.. what is the gene in which one shouldnt take lithium with?
     
  10. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Yasko affirms that those with SHMT and/or MTR/MTRR mutations tend to excrete a lot of lithium in the urine tests. Thats why she recommends it to these. I have those mutations! And anyone with a great need for B12 according to their genes should be on lithium because it helps B12 to be transported to blood cells.

    No idea...
     
    L'engle likes this.
  11. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    What happened with the HC? Did you make sure you had low cortisol before taking it?
     
  12. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    I have been having sub-optimal thyroid function. Both my free T4 and free T3 were very low in ‘normal’ range. My doctor wanted me to take supplemental T4, but I didn’t because of low adrenal function. I did not know that lithium could effect thyroid function, so I started taking lithium orotate on my own. It helps sleep and also keep me calmer during the day.

    The next time my thyroid was checked the free T4 was high normal, but the free T3 was still low normal and reverse T3 was outright high. I have no idea if the lithium had anything to do with this.

    I took a very low dose of supplemental T3 and my free T3 was optimal a month later. My free T4 is low normal, but I think that is expected when taking supplemental T3.

    Have you had your lithium tested? Mine was low, which is why I started supplementing it.
     
    Beyond likes this.
  13. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Amazing Little Bluestem another testimonial for lithium helping to calm the sympathetic nervous activity.

    http://www.theelementsofhealth.com/...ticles-stress/the_autonomic_nervous_syste.pdf
    Nope. I had a hair test done in Spain but it was so shitty it lacked lithium! Anyway I´m quite sure of having this defficiency I have a lot of hints for it. And I have had all kinds of tests showing I was defficient in almost everything :rofl: especially these things that get depleted if you are metal toxic such as Glutathione and other antioxidants (lithium gets depleted in case of neuro/excitotoxicity as it is used to protect the brain).
     
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  14. Dreambirdie

    Dreambirdie work in progress

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    I have written about this experience several times here, and honestly don't want to go into the horror story of it again. HC was BY FAR THE WORST THING I have ever taken. THE WORST.
     
  15. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    My bottle of lithium orotate says that "individuals with renal or cardiovascular disease or who are taking diuretics or ACE inhibitors should consult their health-care professional before use." It also says that it should not be taken by pregnant or nursing women, but I think that is standard.
     
  16. dannybex

    dannybex Senior Member

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    This study seems to suggest that lithium causes an increase in cortisol...?

    "
    Patients had a significantly higher ACTH and cortisol response to CRH stimulation during lithium augmentation compared with the values at baseline."

    http://www.ncbi.nlm.nih.gov/pubmed/12225704

    ???
     
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  17. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    The same guy, T. Bschor, tried a similar study one year later:
    http://www.ncbi.nlm.nih.gov/pubmed/12577277

    And also in 2011! http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027613

    But we have to bear in mind these studies are done probably on lithium carbonate and in much higher doses. However, this is a very significant finding, dannybex.
     
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  18. Ema

    Ema Senior Member

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    If you have Hashi's, I would watch out for iodine because it can cause a flare.

    Ema
     
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  19. Ema

    Ema Senior Member

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    This study used lithium carbonate at 2x 450 mg.

    I have no idea if that is a high dose or not though it sounds like one.
     
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  20. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    Lithium carbonate is a prescription med that is taken at much higher doses than lithium orotate.
     

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