I feel like I've taken every supplement known to humans at one point or another. These days I've narrowed it all down to a few essentials: Ester-C - 1000mg x3 Co-Q 10 - 100mg x2 Gamma E - 400IU Vit. D3 - 2400IU x2 Magnesium - 400mg + whatever I get from Epsom salt foot baths Probiotics - mostly acidophilus & bifidus Zinc carnosine - helps heal stomach lining from gastritis caused by a course of methylprednisolone I had to take once Capillaris Combination - traditional chinese herb formula to help with liver/gall experimenting with Cordyceps - immunomodulator, anti-fatigue, not sure if I'm reacting allergically yet or not melatonin - 3-9mg. I don't tolerate most B vitamins, or I would definitely take those. B5 cranks up my immune system, and B-12 makes me feel a little wired and drains my adrenals. B2 doesn't seem to do anything, but I don't want to take just that or B6 alone and create B imbalances. I'm also folate deficient, but taking folate makes me really depressed for some reason, before it wears off. I think it has to do with methylation pathways.