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ME/CFS: A disease at war with itself
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List of Mastocytosis genes

Discussion in 'Mast Cell Disorders/Mastocytosis' started by taniaaust1, Jul 9, 2014.

  1. taniaaust1

    taniaaust1 Senior Member

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  2. Valentijn

    Valentijn Activity Level: 3

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    @taniaaust1 - I've looked at KIT and KITLG for 12 patients, but haven't looked at the rest. I'll try to do so in the near future, though it might have to wait until my catheter comes out on Friday afternoon.
     
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  3. taniaaust1

    taniaaust1 Senior Member

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    @Valentijn take care of yourself.

    I wish I was far more computer savy. If I was, I think I'd try to make up some kind of program in which those who have ME/CFS could run raw data thou and have results came back as a percentage of how well they match the gene profiles of certain like ME/CFS illnesses (compared with control groups of those illnesss). eg Result you are a 100% match to lyme patients due to having gene ?? ?? ?? or whatever or 86% match to mastocytosis due to having gene ???, or 50% match to EDS patients according to genes or whatever. It would be a very interesting possible diagnostic aid. Maybe it would help too to better pull out CFS subgroups.
     
  4. Valentijn

    Valentijn Activity Level: 3

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    It would be useful, but the problem is that most of the research into genes and ME/CFS are junk so far. Very weak correlations, saying that people with the most common genotype are slightly more likely to be ME patients, etc.

    According to some of those studies, most of the patients I have data for should be relatively safe from developing ME/CFS :rofl:
     
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  5. taniaaust1

    taniaaust1 Senior Member

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    Funny you say that, as Ive been looking for the so called connected ME/CFS genes and so far, none of those have come up for me!! (thou I arent finished looking throu it all yet).

    So maybe we should have more faith in the gene research of OTHER illnesses (I currently trust that more then ours!). I'll tell you when I find one of the so called ME/CFS genes.
     
  6. Valentijn

    Valentijn Activity Level: 3

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    @taniaaust1 - I finally got around to looking at these genes (and some very closely related ones) and putting the image together. It doesn't look there are any significant differences in rates of rarity for the ME patients versus the controls.

    mastocytosis1.gif
    mastocytosis2.gif
     
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