I'm kind of looking at things from a new angle now that I tested positive for antiphospholipid antibodies. This is an autoimmune condition that can cause issues such as DVT, cognitive problems like word recall issues, fatigue, and memory loss. It can also cause issues with organs such as the kidney or bladder. It's a fairly "new" disease, and is also known as antiphospholipid syndrome, and some call it Hughes syndrome. In any case, I've been having what appear to be adrenal issues since my knee surgery last year. There's no doubt my HPA-axis is out of control, however there was a reason for this and it actually makes sense now. I believe the body is responding to the inflammation of destroyed tissues by increasing cortisol which is anti-inflammatory. Also, autoimmune conditions can have high or low cortisol associated with them. My inflammatory markers such as HS-CRP, homocysteine, and sed rate were actually normal. The test I used to determine this was the Cyrex Assay #5.