Can't link, as paywalled, but as follows: Illness in the head? Sir, Your article “What if your illness is all in your head?” (Times2, Apr 27), highlights Suzanne O’Sullivan’s claim that people with myalgic encephalomyelitis (M.E.) are not hypochondriacs, malingerers or crazy, and that they are often profoundly disabled and live miserable lives. These facts are undeniable. What is not true, though, is the assertion by Ms O’Sullivan that M.E. is a psychosomatic illness. We would welcome the chance to see the evidence for this claim. On the contrary, a growing body of research points to the brain abnormalities, inflammation and altered immune response to exercise experienced by people with M.E. What’s needed now is mainstream research funding to build on these studies and develop effective, personalised treatments for people with M.E. Sonya Chowdhury CEO, Action for M.E.