Had my 23andMe done and like most, was concerned with the array of SNPs that were homozygous and heterozygous and what that my mean for my health. Am homozygous for MTHR 1298C and heterozygous for CBS C699T plus several MTRRs, NOS3 and SOD2. Was sure that my Sulfate and Ammonia would be high and my BH4 would be low and perhaps my Glutathione as well. Well the lesson is this: You can have all the messed up SNPs in the world but you have to find out if they are being expressed. And you won't know that unless you follow up with comprehensive testing. I had a NutrEval Plasma, Organix Comprehensive Profile, CDSA, Thyroid and Allergens checked. Turns out my Glutathione is very high and Ammonia / Sulfate are quite good. Oddly, I seem to have an IgG Egg reaction that was off the chart high so bye-bye eggs. Biopterin was high so looks like 1298C is not being expressed. Some dysbiosis with high 3- Hydrophenylacetic Acid and Benzoic Acid. Anyone with knowledge on these, would love to hear from you. Vitamin D moderately low. Isoleucine, Taurine, Succinic Acid - Low A-Linolenic low but EPA and DHA high. Wondering if A-linolenic matters since I thought it is only important for it's conversion to EPA / DHA. What else does A-Linolenic do??? Thoughts on that would be appreciated. Creatinine, urea, threonine, asparagine - High Mercury in the RED in the lower part of the High range - 0.0049. Wondering if detox is in order? Have only 2 really small fillings so I assume this is mostly seafood related. Anyone who's really sharp on NutrEval or the ramifications of any of these readings, would greatly appreciate your insights. Read Rich's piece on NutrEval, which was very informative but if anyone knows further your replies would be invaluable. Learned must from these test. Please go out and get'em for yourselves!