Hello, I was wondering if someone can help me with this. Here are my genetic genie results: https://drive.google.com/drive/folders/0By9VwoUlJRdCakJDQzRuclU1Y2c?usp=sharing For some reason, everytime I take the Life Extension multivitamin I get extreme fatigue and just feel generally depressed, like a big dark cloud wrapped around my brain for lack of a better explanation. Here is the profile (under supplement facts): http://ca.iherb.com/Life-Extension-Two-Per-Day-Capsules-120-Capsules/67037 I suspect it is the B6 (non P5P form). My GG profile isn't that bad according to the SNP interpretation guide on this forum. I just need to ensure adequate vitamin D intake, hydroxy B12, DIM for estrogen, and BH4 supplementation (from where?). I don't experience the CBS symptoms despite being homozygous. Thanks guys! Edit: I should also note that my blood tests reveal that I have slightly elevated B12.