The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Lane, Hosking (2010) The pathogenesis of murine coronavirus infection of the central

Discussion in 'Other Health News and Research' started by WillowJ, Dec 24, 2010.

  1. WillowJ

    WillowJ คภภเє ɠรค๓թєl

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    Lane TE, Hosking MP. "The pathogenesis of murine coronavirus infection of the central nervous system." Crit Rev Immunol. 2010;30(2):119-30. PMID: 20370625

    Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3900, USA.
     
  2. WillowJ

    WillowJ คภภเє ɠรค๓թєl

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    interesting that this starts with an acute infection in mice. That isn't present in human MS, is it?
     
  3. Cort

    Cort Phoenix Rising Founder

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    They have apparently really looked into what triggers relapses in MS - and infections do and stress can - and other things don't. Interesting that some periods of pregnancy appear to be good for MS and others bad - which I think is true for CFS. Here is some information on triggers....from Wikipedia

    http://en.wikipedia.org/wiki/Multiple_sclerosis


     
  4. WillowJ

    WillowJ คภภเє ɠรค๓թєl

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    triggers of relapses are interesting--thanks for doing the search for me (I was lazy last night because it was late). I was interested in initial onset, too.

    WebMD says,
    I found an interesting case report of atypical onset of MS with silent coeliac disease and autoimmune hepatitis; they're saying "inflammatory immune-mediated damage of the CNS triggered by gluten could not be excluded" and MS-like disease with MRI abnormalities is a small subset in coeliacs.
     

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