Lactic (organic) Acid Symptoms - from CFS Australian Study - You'll be surprised!

[Cort]

Check out a questionnaire developed by Bioscreen in Australia to assess symptoms associated with lactic acid (and other organic acid buildup) in the gut. It's very interesting how lactic acid can cause both physiological and 'mood' problems. It really bridges the gap.

Herr's the study from the SACFC Newsletter - the questionnaire is attached

http://sacfs.asn.au/news/2008/03/03_07_lactic_acid_study.htm

Friday 7 March 2008

Dr Ian Buttfield some time ago approached us to see if we would encourage members to volunteer for a research project focusing on lactic acid. The researchers include Dr Henry Butt of Bioscreen in Melbourne and Dr Neil McGregor, both of whom have attended the experts' forums held by the Alison Hunter Memorial Foundation in Adelaide over the last two years.

The research team describes the project thus:

“The purpose of this study is to identify changes in CFS patients by measuring levels of specific chemicals in urine, blood and faeces in a clearly defined group of sufferers. The specific chemicals are ‘organic acids’, especially lactic acid. A further aim of this study is to see if the changes in these organic acids can be related to changes in the bacteria in the gut. Studying and comparing these changes in patients against those from individuals with little or no symptoms may further help to understand the disease.

The ultimate aim is to understand these changes so that they can be corrected with specific treatments which will help improve symptoms for patients.”

The Society’s committee last week agreed to support the project strongly. This is not least because the pool of volunteers for the project is to come from South Australia. Dr Buttfield will conduct simple and non-intrusive blood, urine and faecal tests which will then be processed at Bioscreen in Melbourne.

The committee also decided to contribute $2000 to the project. It’s expected to cost about $8000 or more and the researchers are funding it privately. We appreciate this commitment on their part and wanted to demonstrate that appreciation practically.

The team is awaiting for ethics committee approval, but Dr Buttfield would be delighted to start receiving the names of volunteers now so that all is ready to go as soon as possible after the approval comes through. Here are the contact details: Dr Ian Buttfield (08) 8272 4822.

Documents relate

 

[cfs_confesstothemess]

Astounding on symptom comparison.

 

[Cort]

Who would have thought? With Maes, De Meirleir and Peterson heavily focused on gut issues - and the CAA exploring gut microflora in detail and this study going on the gut is getting pretty darn interesting.....

 

[sleepy237]

I wish I could travel to KDM, seven years ago i tested H PYLORI + was given the triple treatment, a year or so later had endoscopy which showed ulcer scar and duodenitis. I still have very bad acid reflux controlled by Lansoprazole but why it is so bad even with missing my PPI for a few hours is scary, so much acid production. In the months before my first complete crash i was doubling up with abdominal pain outside etc. An ultrasound showed nothing.....When I got out of bed for the first time post onset I tried eat chinese food and instantly blew up like a whale two forkfuls and i was done with MSG for good. A psychiatrist knew what would happen she said the gut is first to dysfunction because it is not necessary for survival (in a crisis) but as time goes on we do need our gut function to return. I think the gut is a very strong associate to the onset and possible disease progression and I hope that KDM provides us with more good news.

 

[sleepy237]

http://www.youtube.com/watch?v=_xFDC8vc9s8&feature=related

Findings of excess acid and early acidisos. I hope that Dr Buttfield can start his research soon. One of phoenix risings members brought this to members attentions weeks ago and it may well be significant. I also hear that lactic acid/d lactic can be TREATED. Thanks Glynis and Cort.

 

[lizw118]

I am assuming that this is more related to D-lactic acid? Or is it both D and L lactic acids?
Thanks
Liz

 

[Glynis Steele]

Liz,

Am I correct in thinking that in a past post, you have stated you have d-lactate in a urine test? PM me if you'd rather.


Glynis

 

[lizw118]

Hi Glynis
Yes, I did post that previously. I had a metametrix ion profile test and the marker for d-lactate came out high from the urine sample I gave them. I had never heard of d-lactic acid before. I also had high markers for sibo in general. Do you have high d-lactic acid levels? I have many of the symptoms on the list in this post, although sometimes I find that many of these symptoms could be from many other things like candida, etc. I never know what is causing what!
Liz

 

[Glynis Steele]

Liz,

I've sent you a PM, with a few case studies and such about d-lactic. Hope they are useful to you. D-lactic acidosis is usually only seen in short bowel patients, but it is being researched as part of CFS, as d-lactic acid producing bacteria were found in stool samples of CFS patients, and in higher amounts than controls. D-lactic is caused by certain bacteria fermenting carbs, and both conditions, d-lactic acidosis and CFS, are said to be striking in similarity.

Take care.

Glynis x

 

[lizw118]

Hi Glynis
Thanks. I got the PM. I thought I would bring up one point here, which is to see if it is actually worth it to even see a g.i. specialist. Wouldn't he or he only be able to offer antibiotics and or steroids? Or would there be some other advantage to seeing a specialist? Anyone know?
Liz

 

[Glynis Steele]

Hi Liz,

If it was found that you had high d-lactate in your blood, a GI is the relevant specialist. A healthy human is not meant to have much d-lactate 0.0-0.25mmol/L being normal. It is seen as a serious condition, in short bowel patients, and a patient with high d-lactate needs specific treatment, and monitoring of the d-lactate, until it returns to normal levels. It would be negligent on the GI's part, if a person with d-lactate was left untreated. Yes, abx is part of the treatment. It can be a trial and error, getting the right abx, depending on what the gut bacteria are resistant to, but it would need treatment with abx, sometimes IV sodium bicarbonate too, and if d-lactate recurrs, a low carb diet is usual.

Hope this helps

Glynis x