After reading Fredd's protocol, I realized I needed to drop the amount of methylfolate I was taking, increase methylcobalamin and start taking potassium. However, in the last few days that I have tried this my appetite went from normal to ridiculously insatiable, eating 3000 calories + a day and still feeling hungry. I have the same problems to if I take magnesium or calcium. I tried taking magnesium a few months ago but I couldn't deal with the appetite change. To put things into context, I have c677t homo and pyroluria. Diagnosed extremely low zinc. Been supplementing for 2-3 months and testing out what works. Does anyone know what the hell is going on?