Hi! I spend a lot of time reading in mast cell support groups (facebook and so on) and I rarely met a person who does not have something like: - fibro - cfs - mcs - eds - autism The mast cell activation seems so extremley common in these folks. I don't think mast cell activation is the main reason for these symptoms in most of the people, I think it's the other way around and so many faulty metabolism pathways lead to the development of mcad. But I am always wondering about the "common denominator" of the mcad. Is it low adrenal function? Immune dysregulation? Dysregulation of the nervous system...? What are your thoughts about it?