Ok I have started yesterday on the simplified protocol. I took one multi yesterday and slept well. Today I have taken 2 multis, 2 drops b12 and 1/4 folinic capsule. About an hour after the folinic my ankles started hurting, this spread to my feet, knees, calves, wrists, elbows and finally hands. The discomfort is typical of my old fibromyalgia pain, which I don't get anymore. Strangely I feel mentally much more alert than usual it's gone 10pm and I'm not yawning! My other half asked me to explain why I was getting the old pains back and I couldn't give him a decent explan. What is likely going on in my body? I took the methylation panel btw and awaiting results. I did have very low cq10 and glutathione in previous testing so sure methylation is gonna be an issue. Thanks.