I have been coming to this board since early in 2010 lumbered with a diagnosis of Fibromyalgia and probable M.E.....and that may still be the case! My earliest symptom diagnosed unequivocably as a stand alone condition one week before getting very ill, was peripheral neuropathy. Exactly one week later on the 3rd of August 2007, whammo - extreme fatigue (four months in bed), nausea, joint pain, muscle pain and many, many other symptoms which I'd have to check my notes for. Most of my symptoms have been referenced in the literature as related to M.E. and to some extent Fibromyalgia, including a diagnosis checked off against the CCC. Over the time since diagnosis I have as able, researched my individual and collective symptoms....yet some of my symptoms were not often mentioned for instance on this board, which always left me with an element of doubt. Also many say that these conditions are a wastebasket diagnosis or similar, so one tends to keep ones antennae up looking, just in case something has been missed. Does anyone else do this? Well last week I went to my very experienced M.E./CFS specialist doctor (only second time I've seen him) and I innocently told him I had two new symptoms which had emerged since I last saw him in September. I told him that my mouth was peeling skin everyday from around the gums and palate and the skin of my mouth felt rough. He looked at me intently and asked me how my eyes were. I mentioned that my vision is often blurry, eyes often feel gritty and irritated and have had heavy eyelids off and on for four years now. He then said he felt that I probably had Sjgren's Syndrome and after a moment of being taken aback, I then thought, no big deal.......dry mouth and dry eyes that's ok, nothing compared to what I've had. Then I started to think....what if??? So back to doing some more research, this time on the specific symptoms ofSjgren's and what do I find? Dry mouth and dry eyes the least of my symptoms and worries relatively speaking (but progressive evidently - something to look forward to.... yuck) ....however just a little digging and I find peripheral neuropathy to be one of the non-glandular symptom. So too are problems like gastroparesis, swallowing and gut problems! Over active bladder too......and ......until five minutes ago I felt that one other symptom I have - orthostatic intolerance didn't fit but I just read this "Orthostatic symptoms related to dysfunction of autonomic control of blood pressure and heart rate is associated with increased severity of Sjgren syndrome". Phew I thought I'd have to come off the beta blockers which are very effective. So although the online sites and literature tend to labour the dry eyes and mouth (which are essential components) the people with more severeSjgrens can have many other symptoms as it is an autoimmune condition which can affect many organs (multisystem). Also paradoxically....perhaps....I read "Reports on the use of rituximab in patients with primary Sjgren syndrome have emerged in the literature". (sorry too late to put in my references but can if anyone wants them). So although this diagnosis is not confirmed yet it explains a lot of things. Perhaps Dr Hyde and others who say that a fair percentage of people withthe diagnosis of M.E./Fibromyalgia really have other undiagnosed conditions are quite correct. I'm beginning to see that is possible although I did not expect that outcome for myself, as I got tested for almost everything four years ago.