It's a shame that this information is hidden in an obscure thread in this forum. I wish I could put it in a permanent website that always goes top of google results and is translated in every language for everyone to see. Goodness knows what harm has been done to newly diagnosed people. I saw a doctor/researcher yesterday who has the power to ask the ministry of health where I live to make a special case for me to receive Rituximab as a one off case. Before I could bring it up the doc goes into the exact PACE thing that is quoted above. He believes it, and even if he didn't he would probably have to recommend it anyway because CBT is the official recommended treatment for CFS/ME. CBT is in most of the fibro and CFS research papers he reads, other than Cymbalta and Lyrica which were unhelpful for me. He offered to get me Rituximab at the end but I have no desire to try this experimental drug with someone so ignorant. This information you've all got together should really not be stuck in this thread alone.