The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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is sCD14 test good for leaky gut?

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by Daffodil, Apr 18, 2015.

  1. Daffodil

    Daffodil Senior Member

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    hi all. i just read an article on an HIV website, that says:

    Beyond bacteria
    Researchers in San Francisco have conducted elegant and sophisticated experiments to try to understand why monocytes produce sCD14 even in HIV-positive people who do not have bacterial infections. As part of this work, they took blood samples from both HIV-positive and HIV-negative people for analysis.

    They found that monocytes from HIV-positive people seem to be activated because of exposure to interferon-alpha and not bacteria or bacterial proteins. Furthermore, activation of monocytes in their experiments resulted in the release of sCD14. The activation of monocytes in their experiments stemmed from exposure to HIV.

    Other researchers in London, UK, have found that persistent activation of another group of cells—natural killer (NK) cells, which can help fight HIV-infected cells and cancers—occurs in people with HIV. This activation did not occur because of bacterial infections.

    --------------------------------
    quoted from this article:

    http://www.catie.ca/en/treatmentupd...tion/importance-soluble-cd14-and-inflammation
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    does this mean something other than leaky gut (viral activation, for example) can cause high sCD14?

    i cannot find the san fran study they are referring to
     
    Last edited: Apr 19, 2015

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