I wasn't sure where to post this. Sorry if it is in the wrong place. I was looking at these two studies today: http://www.sciencedirect.com/science/article/pii/0306453092900172 http://www.sciencedirect.com/science/article/pii/S0889159115300209 I started thinking about diabetes and Americans in particular. We tend to be overweight as we age and eat more sugar than the average person somewhere else. We have a high rate of diabetes possibly because our bodies are always producing insulin and we become insulin resistant. We also use more antidepressants than most other societies. Antidepressants work by being norepinephrine and serotonin reuptake inhibitors, correct? Thereby, keeping more free flowing serotonin and norepinephrine in our blood. Could the immune system react to that and start attacking serotonin and adrenal receptors? Is this possible? I am also wondering if treatment for Fibromyalgia with Antidepressants like Savella could eventually make Fibromyalgia and CFS symptoms worse.