First of all, I know we've had some death related to CFS/ME lately, but in the vast majority it's not fatal. Second, we don't see illnesses like HIV going into remission just by following protocol X or Y developed in a forum. (even with everything they already know) Third, normally in CFS/ME people's health slowly deterioarte because they're not receiving treatment (well.. it's a illness after all) I think it's safe to say even with the worst investment ever in a disease, there are amazing doctors developing treatments and coming to conclusions, as well as studies showing new promissing info everytime. So am I too optmist to think the cause of CFS/ME and FMS is a weak something (virus, bacteria or wathever)? It looks like if 1/3 of the investment that goes to HIV went to CFS/ME/FMS the puzzle would be solved in a blink.