Hi Legendrew, thanks for sharing. Yes as you say its difficult to work out what is causing what sometimes. My ME was triggered by vaccines too - Hep B in my case...it was following my 4th jab/booster that I caught a viral ear infection, which led onto ME...I never recovered and that was 20yrs ago! I only tried abx the last few yrs since testing positive to various infections eg lyme, cpn and I have to say that they have been the most helpful treatment overall that Ive tried, though as I said the side effects became difficult to tolerate so I decided to stop. Though the fact that I experienced significant improvement does seem to suggest that I have various chronic infections....I dont know if this means the infections are at the root of the illness or as Prof Edwards says maybe as a result of immune dysregulation. I know that vaccines can trigger immune dysfunction and i wonder if either they are contaminated themselves, or disturb the body's ecology, and/or reactivate dormant infections? Who knows. There is some research that suggests that the Hep B vaccine in particular, can trigger demyelinating diseases via molecular mimicry.