http://www.bmj.com/content/354/bmj.i5191 This seems almost tailor-made for the emerging problems with PACE and its impact on guidelines. Both the Cochrane collaboration, US and UK guidelines are (to varying strengths) heavily reliant on PACE and the subsequent first data release. Highlighting the fact that severe CFS patients will suffer would be nice, but I don't think there is robust evidence for that yet. PACE - even on the authors own recent reanalysis is a much smaller effect size for CBT over standard care, which vanishes entirely into statistical insignificance after looking at the reanalysis by others. Highlighting this, and throwing a bone to the CBT people that it may somewhat help with anxiety and sleep, but is not measurably effective on any other measure would seem solidly within the remit of this rapid 'new evidence' process. http://help.magicapp.org/knowledgeb...rganization-is-non-profit-do-i-have-to-pay-an - non profits seem also to be able to have some input, though I have not investigated properly exactly what.