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Interferon Gamma, Mitochondria, and T2 Diabetes.

Discussion in 'Other Health News and Research' started by Ema, Apr 2, 2014.

  1. Ema

    Ema Senior Member

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    So, interferon gamma is bad for the mitochondria but it is intricately involved with the immune system response.

    And may play a role in the development of Type 2 diabetes...

    http://nar.oxfordjournals.org/content/40/4/1609.full-text-lowres.pdf
     
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  2. Bob

    Bob

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    MeSci and Valentijn like this.
  3. Ema

    Ema Senior Member

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    I'll have to go back and find the exact reference but there is also something to high levels of interferon gamma in patients who go on to develop chronic Lyme disease versus those who are able to rid themselves of the infection after a more typical course of antibiotics.

    There seems to be something in the way the innate immune system reaction transfers (or doesn't transfer) to the adaptive immune system reaction that predisposes to chronic illness and it seems that interferon gamma may be a big player.
     
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  4. Dan_USAAZ

    Dan_USAAZ

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    I believe high levels of IFN-g are also implicated in MS as causing demyelination of the myelin sheath around nerves.
     
    Last edited: Apr 3, 2014
  5. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    I've just started a new thread on interferon and depression that may be of interest.
     

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