Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Insitol hexanicotinate interfere with methylation?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Adlyfrost, Oct 30, 2014.

  1. Adlyfrost

    Adlyfrost Senior Member

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    NJ
    This is also called no-flush niacin. Would like to take a supplement with 75mgs per serving but not sure.
     
  2. traray

    traray

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    I like your question and was hoping someone would answer.....I take this occasionally combined with choline and have wondered if it was a good idea.
     
  3. Little Bluestem

    Little Bluestem All Good Things Must Come to an End

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    Would that be inositol hexanicotinate? I take a supplement that just says 'inositil'. It is a form of niacin that is also sometime called B9. Mine are 750 mg capsules, so it may not be the same thing.
     
  4. adreno

    adreno PR activist

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    I don't believe such a small dose of B3 would interfere. However, you might want to take your methyl supps in the morning, and the B3 in the evening.
     
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  5. adreno

    adreno PR activist

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    I believe you're thinking of Inositol Hexaphosphate (IP-6), this is not a form of B3.
     
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  6. whodathunkit

    whodathunkit Senior Member

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    @Adlyfrost: In my experience any little bit of *any form* of supplemental niacin can interfere with methylation, at least when I was starting out. I tried all forms, including inositol hexanicotinate. Even really, really small amounts of niacin would cause me problems. Even a small amount of of the so-called "active" form NADH, which supposedly is symptom-free because it requires no processing in the body for the body to use it.

    I have to do my B vitamins piecemeal to avoid niacin completely. I'm thinking about trying some again, however, since I'm much more stable than I used to be. We'll see.

    Worth noting is that I do drink milk and eat unrefined whole grain, so it could be that I am getting enough niacin from my food and didn't need any supplemental.

    But you asked was it possible and yes, IME it is possible. Plus, 75mg seems like a big dose
     
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